Jon Horvitz

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Jon Horvitz
This page is for those with a background in neuroscience and an interest in the neurobiology of motivation and reward-based learning. Below will be suggested readings on basal ganglia function, cortical assemblies, dopamine, and other issues relevant to the neurobiology of motivation. This is under development.

Some of the readings deal with concepts that may be unfamiliar, even to those with neuroscience background. (If you're like me, your expertise drops off quickly as you move to topics a bit outside your research focus.) I'll give relevant background about some of these concepts on this page.

How does the cortex select actions?

  • Wise (1985). The primate premotor cortex: past, present, and preparatory. Annu Rev Neurosci, 8, 1-19. doi: 10.1146/
  • Tanji (2001). Sequential organization of multiple movements: involvement of cortical motor areas. Annu Rev Neurosci, 24, 631-651. doi: 10.1146/annurev.neuro.24.1.631
  • Murakami et al. (2014). Neural antecedents of self-initiated actions in secondary motor cortex. Nat Neurosci, 17(11), 1574-1582. doi: 10.1038/nn.3826
  • Yang et al. (2016). Origins of choice-related activity in mouse somatosensory cortex. Nat Neurosci, 19(1), 127-134. doi: 10.1038/nn.4183

What are neuronal ensembles/assemblies?

  • Tsodyks et al. (1999). Linking spontaneous activity of single cortical neurons and the underlying functional architecture. Science, 286(5446), 1943-1946. doi: 10.1126/science.286.5446.1943
  • Yuste (2015). From the neuron doctrine to neural networks. Nat Rev Neurosci, 16(8), 487-497. doi: 10.1038/nrn3962

What are computational approaches to reinforcement?

  • Sutton, M. A., & Barto, A. G. (1998). Reinforcement Learning: An Introduction: MIT Press.

What is epigenetics?

  • Sweatt, J. D. (2013). The Emerging Field of Neuroepigenetics. Neuron, 80(3), 624-632. doi: 10.1016/j.neuron.2013.10.023